Basic Phenergan Information

• INN (International Nonproprietary Name): Promethazine hydrochloride
• Brand names available in Canada: Phenergan, Avomine, Fargan
• ATC Code: R06AD02
• Forms & dosages: Tablets (10mg, 25mg), Elixirs (1mg/mL)
• Manufacturers in Canada: Various manufacturers, typically through local distributors
• Registration status in Canada: Registered as a prescription medication
• OTC / Rx classification: Prescription-only in most cases

Availability & Price Landscape

How accessible is Phenergan in Canada and what does it cost? These questions matter, especially for those needing this medication for allergies, motion sickness, or other conditions. The availability of Phenergan, primarily in the form of tablets and elixirs, varies at major pharmacy chains.

Major National Pharmacy Chains

When looking for Phenergan at national pharmacy chains like Shoppers Drug Mart, Rexall, and London Drugs, customers can generally find both tablet and elixir forms. Stock levels can fluctuate based on demand and regional prescription requirements. It's important to note that while Phenergan can sometimes be bought without a prescription in some provinces, most pharmacies require a prescription for this medication.

Major pharmacy chains often compete on pricing. They may offer discount programs for customers with insurance, which can impact overall costs. A price comparison might reveal slight differences; for example, Shoppers Drug Mart might feature promotional discounts during particular seasons, while competitors like Rexall could have loyalty programs that benefit frequent purchasers.

Online Pharmacy Trends in Canada

<pThe rise of online pharmacies is transforming how Canadians access medications like Phenergan. The convenience of shopping from home appeals to many. However, it's vital to consider provincial restrictions when purchasing pharmaceuticals online. Certain provinces may have rules governing the sale and shipping of medications, which can affect availability.

Additionally, prices found online can vary starkly compared to traditional pharmacy settings. While some online platforms offer competitive pricing for Phenergan, there are often shipping fees that can negate the discounts. Always ensure that the online pharmacy is reputable and complies with provincial regulations.

Price Ranges by Package Size

Understanding the cost of Phenergan can help in planning for treatment. Price ranges for Phenergan generally depend on the dosage form and province of purchase. For instance, in Ontario, the price for a pack of 25mg tablets can range from $7 to $15, while 10mg tablets are typically sold at a lower rate, approximately $5 to $10. The cost may differ in provinces like British Columbia or Alberta due to local pricing policies and drug coverage programs such as the Ontario Drug Benefit.

Overall, the average cost may fluctuate based on local demand, insurance coverage, and pharmacy loyalty programs. Optimizing choices can lead to savings and better accessibility to medication when needed. Always consult your pharmacist for more information about pricing and availability tailored to your region.

How It Works in the Body

Layman’s explanation

Phenergan, also known as promethazine, is an antihistamine that works by blocking certain natural substances in the body, like histamine. Histamine typically triggers allergy symptoms such as a runny nose, sneezing, and itchy eyes. By blocking this chemical, Phenergan helps alleviate these uncomfortable symptoms, making it a go-to choice for allergy sufferers.

In addition to treating allergies, Phenergan is effective for motion sickness. It helps prevent nausea and vomiting during travel by acting on the brain's receptors that trigger these symptoms. By stabilizing these signals, patients can enjoy a smoother ride without the discomfort of motion sickness.

Clinical detail from Health Canada resources

From a clinical perspective, Phenergan works through its pharmacodynamics, impacting the central nervous system and peripheral tissues. It has an absorption rate of approximately 25% when taken orally, with peak plasma concentrations reached within 1 to 2 hours post-ingestion.

The half-life of Phenergan is between 10 to 19 hours, which can vary significantly based on individual metabolic factors. Liver function, age, and overall health can affect how the body processes Phenergan, highlighting the importance of personalized dosing regimens.

Dosage & Administration

Standard regimens per Canadian guidelines

According to Canadian guidelines, the standard dosage for adults varies between 10 mg to 25 mg, taken as needed. For children aged six and older, the dosing typically ranges from 5 mg to 15 mg at night or divided throughout the day. Dosing is adjusted based on individual symptoms and responses, ensuring the safest and most effective use.

Patients should remain mindful that younger populations, along with the elderly, require special attention when determining appropriate doses. Adjustments might be necessary, given the increased sensitivity to medication side effects in these groups.

Adjustments by patient type

When prescribing Phenergan, factors like age, weight, and general health status must be considered. For instance, children under two years should not use Phenergan due to a heightened risk of severe respiratory depression.

The elderly population also requires careful dosing adjustments as they may experience increased sensitivity to both the effects and side effects of the medication. It's not uncommon for healthcare providers in different provinces to have varying practices based on local guidelines.

Contraindications & Side Effects

Common

Several contraindications exist for Phenergan. Health Canada identifies hypersensitivity to promethazine or any phenothiazine derivatives as a primary concern. Children under two years are advised against using Phenergan due to substantial risks.

In older adults, close monitoring is crucial, as this group might encounter adverse reactions more frequently; this is particularly pertinent for those with existing health issues.

Rare but serious

Some rare, yet serious side effects have been noted in Canadian pharmacovigilance data. Reports include severe respiratory issues, significant drowsiness, and instances of confusion, especially in the elderly.

Monitoring for such adverse reactions is essential. Health Canada stays vigilant by tracking and reviewing these occurrences, ensuring patient safety remains a priority.

Comparable Medicines in Canada

Alternatives table

<th DIN

Medication	Indication
Chlorphenamine	[DIN specific]	Allergy relief
Diphenhydramine	[DIN specific]	Sleeping aid, allergies
Cetirizine	[DIN specific]	Nasal allergies
Loratadine	[DIN specific]	Non-sedating allergy relief

Pros and cons list

When comparing Phenergan to its alternatives, a few key pros and cons arise:

• Pros: Effective for a wide range of symptoms, including allergies and motion sickness.
• Cons: Sedation is a common side effect, which may not be suitable for everyone.
• Pros: Available in multiple formulations (tablets, elixir).
• Cons: Requires careful dosing adjustments for sensitive populations.

Current Research & Trends

Research into Phenergan (promethazine) continues to shape its applications in Canada and globally. Key studies and findings from 2022 to 2025 highlight several interesting trends. For instance, recent Canadian medical conferences have showcased increasing interest in the medication’s role in managing nausea, particularly in pregnancy and post-operative care. Innovative administration methods, including Elixir and newer formulations, have also emerged, catering to specific patient demographics and their unique needs.

Additionally, studies reveal that Phenergan continues to be prescribed for various conditions beyond allergy relief, notably for sedation in pre-operative settings and as a safe alternative for motion sickness. Noteworthy is its growing recognition in treating insomnia and sleep disturbances, thereby expanding its therapeutic range.

Common Patient Questions in Canada

Patients across Canada often have questions regarding Phenergan, from its uses to safety measures. Below are frequent inquiries:

• What is Phenergan used for?

  Primarily prescribed for allergies, motion sickness, and as a sedative, Phenergan is effective in combating nausea and vomiting.

• Is Phenergan safe for children?

  While used in pediatric cases, caution is advised for children under 2 due to potential respiratory risks. Consult a pediatrician for appropriate dosing.

• Can I use Phenergan for sleep?

  Yes, it can be prescribed for sleep disturbances, but it should be done under medical supervision to avoid dependency issues.

• Are there any side effects?

  Common side effects include drowsiness, dizziness, and dry mouth. Seek medical attention for severe reactions.

• Is it available over-the-counter in Canada?

  No, Phenergan typically requires a prescription, but in some cases, may be obtained without one depending on the jurisdiction.

Regulatory Status

Health Canada approval process

Health Canada's approval process for Phenergan involved extensive evaluation of its safety and efficacy. These regulations ensure only high-quality medications reach the Canadian market. The evaluation includes clinical trials, data on side effects, and long-term impact assessments. This thorough vetting process assures healthcare providers and patients that Phenergan meets national standards.

DIN number relevance

In Canada, the Drug Identification Number (DIN) is crucial for medication authenticity. It helps patients and healthcare professionals verify that they are receiving approved medicines, like Phenergan. When purchasing at pharmacies, checking the DIN ensures compliance with Canadian regulations, providing peace of mind regarding medicinal quality and safety.

Visual Recommendations

Infographic ideas for Canadian context

Creating infographics tailored to the unique Canadian context can significantly enhance understanding of Phenergan. Potential topics include:

• Responsible use of Phenergan, highlighting dosages for various conditions.
• Storage recommendations specific to Canadian climates, focusing on temperature and humidity control.
• Visual guidelines on recognizing side effects and when to seek help.

When designing, incorporating elements such as the maple leaf or regional symbols can foster a sense of local engagement.

Buying & Storage Advice

In-store vs. online Canadian purchase tips

When considering where to buy Phenergan, both in-store and online options exist in Canada. In-store purchases can provide immediate availability, but checking with local pharmacies is advised. Factors to consider include:

• Provincial regulations regarding prescription requirements.
• Insurance coverage that may lower out-of-pocket costs.
• Price-matching programs at local pharmacies.

Online purchases offer the convenience of home delivery but should be done through reputable pharmacies adhering to Health Canada regulations.

Proper storage with Canadian climate considerations

Keeping Phenergan safe requires attention to storage conditions. In Canada, varying climates present unique challenges. Key storage tips include:

• Store below 30°C (86°F) to maintain efficacy.
• Avoid direct sunlight, which can degrade the medication.
• Keep out of reach of children and ensure containers are tightly sealed.

These steps are vital in preventing spoilage and ensuring safe usage.

Guidelines for Proper Use

Canadian doctor/pharmacist advice style

Prior to using Phenergan, consulting with a healthcare professional is essential. Monitoring reactions during the initial administration phase is crucial, particularly for sensitive individuals.

It's vital to follow prescribed dosages strictly and have open discussions with doctors or pharmacists regarding potential interactions with other medications or health conditions. Regular follow-ups can help safely manage any adverse effects and ensure effective treatment outcomes.

City	Region	Delivery time
Toronto	Ontario	5–7 days
Vancouver	British Columbia	5–7 days
Montreal	Quebec	5–7 days
Calgary	Alberta	5–7 days
Ottawa	Ontario	5–7 days
Edmonton	Alberta	5–7 days
Halifax	Nova Scotia	5–9 days
Victoria	British Columbia	5–9 days
Winnipeg	Manitoba	5–9 days
Quebec City	Quebec	5–9 days
Hamilton	Ontario	5–9 days
London	Ontario	5–9 days
Oshawa	Ontario	5–9 days
St. John's	Newfoundland	5–9 days